1-Trimethylsilyl-2-Pyrrolidinone

• CAS: 14468-90-7
• Catalog Number: ACM14468907
• Category: Other Products
• Molecular Weight: 157.29 g/mol
• Molecular Formula: C7H15NOSi
• Synonyms: N-Trimethylsilylbutyrolactam; N-Trimethylsilyl-2-pyrrolidone
• Application: 1-Trimethylsilyl-2-Pyrrolidinone serves as a crucial fine chemical intermediate playing a vital role in various chemical synthesis processes It is typically synthesized by refluxing a combination of 2-pyrrolidinone triethylamine and trimethylchlorosilane in benzene This compound is particularly valued for its ability to undergo sulfenylation with phenyl disulfide resulting in the formation of the corresponding bissulfide as the predominant product
• Storage: Moisture Sensitive. Ambient temperatures.

Synthetic Use

Upstream Synthesis Route 1

• 616-45-5
• 75-77-4

• 14468-90-7

Reference: [1]Hua, Duy H.; Miao, Shou Wu; Bharathi, S. Narasimha; Katsuhira, Takeshi; Bravo, Ana A.
[Journal of Organic Chemistry, 1990, vol. 55, # 11, p. 3682 - 3684]

Downstream Synthesis Route 1

• 14468-90-7
• 74-88-4

• 2555-05-7
• 4831-43-0

Reference: [1] Patent: WO2011/75699, 2011, A2, . Location in patent: Page/Page column 140-141

Downstream Synthesis Route 2

• 14468-90-7
• 74-88-4

• 2555-05-7

Reference: [1] Synthetic Communications, 1988, vol. 18, # 4, p. 1625 - 1636

Downstream Synthesis Route 3

• 14468-90-7

• 15166-68-4

Reference: [1] Journal of Organic Chemistry, 1990, vol. 55, # 11, p. 3682 - 3684

Downstream Synthesis Route 4

• 5926-26-1
• 14468-90-7

• 84900-45-8

Reference: [1]Kramarova, V.P.; Shipov, A.G.; Baukov, Yu.I.
[Journal of general chemistry of the USSR, 1992, vol. 62, # 11.2, p. 2113 - 2119][Zhurnal Obshchei Khimii, 1992, vol. 62, # 11, p. 2559 - 2567]

Downstream Synthesis Route 5

• 14468-90-7
• 33402-75-4

• 65556-02-7

Reference: [1]Journal of Organic Chemistry,1981,vol. 46,p. 3040 - 3048

* For details of the synthesis route, please refer to the original source to ensure accuracy.