1-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole 95+%

• CAS: 1107627-01-9
• Catalog Number: ACM1107627019
• Category: Other Products
• Molecular Weight: 258.12
• Molecular Formula: C₁₄H₁₉BN₂O₂
• Synonyms: AGN-PC-0CXM68, SureCN13028373, MB19355, 1-METHYL-1H-BENZIMIDAZOLE-6-BORONIC ACID PINACOL ESTER, 1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzimidazole, 1-METHYL-6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-BENZO[D]IMIDAZOLE, 1-METHYL-6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-BENZO[D]IMIDAZOLE, 1107627-01-9
• IUPAC Name: 1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzimidazole
• Canonical SMILES: B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)N=CN3C
• InChI Key: HOCIEDFQOUYLSF-UHFFFAOYSA-N
• Exact Mass: 276.16500
• H-Bond Acceptor: 3
• H-Bond Donor: 0

Synthetic Use

Downstream Synthesis Route 1

• 1107627-01-9
• 1616099-18-3

• 1616096-91-3

Reference: [1]Current Patent Assignee: EPIZYME, INC. - WO2014/100695, 2014, A1
Location in patent: Paragraph 00362

Downstream Synthesis Route 2

• 1107627-01-9
• 1616099-19-4

• 1616096-92-4

Reference: [1]Current Patent Assignee: EPIZYME, INC. - WO2014/100695, 2014, A1
Location in patent: Paragraph 00364
[2]Duncan, Kenneth W.; Rioux, Nathalie; Boriack-Sjodin, P. Ann; Munchhof, Michael J.; Reiter, Lawrence A.; Majer, Christina R.; Jin, Lei; Johnston, L. Danielle; Chan-Penebre, Elayne; Kuplast, Kristy G.; Porter Scott, Margaret; Pollock, Roy M.; Waters, Nigel J.; Smith, Jesse J.; Moyer, Mikel P.; Copeland, Robert A.; Chesworth, Richard
[ACS Medicinal Chemistry Letters, 2016, vol. 7, # 2, p. 162 - 166]

* For details of the synthesis route, please refer to the original source to ensure accuracy.