1-Boc-3-iodo-7-azaindole

• CAS: 192189-18-7
• Catalog Number: ACM192189187
• Category: Other Products
• Molecular Weight: 344.14829
• Molecular Formula: C₁₂H₁₃IN₂O₂
• Synonyms: 1-Boc-3-iodo-7-azaindole;3-Iodo-pyrrolo[2,3-b]pyridine-1-carboxylic acidtert-butyl ester
• IUPAC Name: tert-butyl 3-iodopyrrolo[2,3-b]pyridine-1-carboxylate
• Canonical SMILES: CC(C)(C)OC(=O)N1C=C(C2=C1N=CC=C2)I
• InChI Key: YNWXYUIDHAWPLF-UHFFFAOYSA-N
• Boiling Point: 397.3ºC at 760 mmHg
• Flash Point: 194.1ºC
• Density: 1.65g/cm³
• Exact Mass: 344.00200
• Hazard Statements: Xi
• H-Bond Acceptor: 3
• H-Bond Donor: 0

Synthetic Use

Upstream Synthesis Route 1

• 24424-99-5
• 23616-57-1

• 192189-18-7

Reference: [1] Organic and Biomolecular Chemistry, 2011, vol. 9, # 9, p. 3139 - 3141

Upstream Synthesis Route 2

• 271-63-6

• 192189-18-7

Reference: [1] Journal of Medicinal Chemistry, 1997, vol. 40, # 15, p. 2430 - 2433

Upstream Synthesis Route 3

• 24424-99-5
• 23616-57-1

• 192189-18-7

Reference: [1]Journal of Medicinal Chemistry,2019,vol. 62,p. 4915 - 4935

Downstream Synthesis Route 1

• 192189-18-7
• 25015-63-8

• 942070-47-5

Reference: [1] Organic and Biomolecular Chemistry, 2011, vol. 9, # 9, p. 3139 - 3141
[2] Organic and Biomolecular Chemistry, 2011, vol. 9, # 14, p. 5129 - 5136
[3] European Journal of Organic Chemistry, 2011, # 24, p. 4532 - 4535
[4] Journal of Medicinal Chemistry, 2017, vol. 60, # 23, p. 9470 - 9489

* For details of the synthesis route, please refer to the original source to ensure accuracy.