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Structure

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

CAS
69304-37-6
Catalog Number
ACM69304376-1
Category
Silylation Reagents
Molecular Weight
315.43
Molecular Formula
C12H28Cl2OSi2

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Specification

Synonyms
TIPDSiCl2
Boiling Point
70 °C(0.5 mmHg)
Flash Point
110 °C
Density
0.986 g/mL
Application
13-Dichloro-1133-tetraisopropyldisiloxane serves a crucial role in biochemical applications primarily as a silylating agent that enables the simultaneous protection of 3'- and 5'-hydroxyl groups in ribonucleosides It facilitates the analysis of Watson-Crick and Hoogstein base pairing in nucleotides and is integral to the development of chemical delivery systems for ribavirin Additionally this compound acts as a protecting group for open-chain polyhydroxy compounds aiding in the preparation of cyclic bridged peptides Its design takes advantage of the significantly faster reaction rate of triisopropylsilyl chloride with primary alcohols over secondary ones ensuring efficient silylation and protection of specific functional groups within molecules
Storage
Moisture Sensitive
HS Code
Hazardous for shipping
MDL Number
MFCD00009655
Packaging
5 g
Physical State
Liquid
Refractive Index
1.454
Signal Word
Danger
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