Siloxane compounds contain oxygen elements, silicon elements, hydrogen elements and carbon elements, which are important industrial raw materials. As one of important siloxane compounds, methoxytriethyleneoxypropyltrimethoxysilane (CAS No: 132388-45-5) has a wide range of applications and shows the advantages of favorable price and low toxicity when compared with other siloxane compounds. The wide range of applications makes it a versatile tool for researchers and its favorable price and low toxicity make it easy to obtain and safe to use in laboratory settings. The common applications and some novel applications (such as its application in Li-ion batteries and highly water-repellent surfaces) of methoxytriethyleneoxypropyltrimethoxysilane are listed below.
Methoxytriethyleneoxypropyltrimethoxysilane can form covalent bonds with the polymer chains, creating a three-dimensional structure that is more resistant to degradation. Thus, it is frequently used as a crosslinking agent in polymers. Methoxytriethyleneoxypropyltrimethoxysilane provides the abilities of reducing friction between surfaces and resistance to adhesive. So, it can be used as a lubricant in many applications, allowing for smoother operation. In addition, it can reduce the surface tension of liquids and thus as a surfactant which allows liquids spread more easily. Moreover, methoxytriethyleneoxypropyltrimethoxysilane can act as a fuel additive to increase the combustion efficiency of fuels and improve fuel economy.
In recent years, researchers are continually seeking the ways to improve the interface stability of electrodes and electrolytes under high pressure, because it is the key to successfully obtaining high energy density lithium-ion batteries. Lately, methoxytriethyleneoxypropyltrimethoxysilane was confirmed as a novel multifunctional electrolyte additive that can effectively stabilize the interface of both Ni-rich layered LiNi0.85Co0.1Mn0.05O2 (NCM851005) cathode and graphite anode in a full-cell by Pham and coworker [1]. This because methoxytriethyleneoxypropyltrimethoxysilane forms a stable and thin surface protective film on the NCM851005, containing Si species, which effectively reduced crack formation, metal-dissolution, and structural degradation of the cathode. And it also forms a stable solid electrolyte interface layer on the graphite anode, stabilizing graphite structure and preventing thickening of the solid electrolyte interface. The study proved that methoxytriethyleneoxypropyltrimethoxysilane had a potential to help the realization of high energy density Li-ion batteries through enabling wider working voltage range for Ni-rich oxide cathodes.
Scheme 1. Schematic representation of interfacial phenomena occurring in the graphite‖ NCM851005 full-cells, cycled between 3.0 and 4.25 V with methoxytriethyleneoxypropyltrimethoxysilane additive.
* MTE-TMS is abbreviation of methoxytriethyleneoxypropyltrimethoxysilane
Lately, Nakamura et al., have successfully fabricated smooth, transparent, and hydrophilic pegylated organosilanes derived hybrid films by using a simple sol-gel reaction of PEGn-Si and tetraethoxysilane (PEGn-Si refers to CH3O-(C2H4O)n-C3H6-Si(OCH3)3, where n = 3, 6-9, 9-12. And when n is 3, the PEGn-Si is methoxytriethyleneoxypropyltrimethoxysilane) [2]. The organosilanes derived hybrid films showed excellent water sliding/removal properties. Although, the water sliding/removal properties of organosilanes hybrid film made by methoxytriethyleneoxypropyltrimethoxysilane are not as good as the films made by other two kinds of organosilanes, the methoxytriethyleneoxypropyltrimethoxysilane hybrid film still shows good performance. It is expected that this kind of water-removal surfaces will replace perfluorocarbon-based water-repellent surfaces, which will help reduce environmental damage.
Scheme 2. Schematic representation of the preparation process of hydrophilic pegylated organosilanes derived hybrid films by using a simple sol-gel reaction of PEGn-Si and tetraethoxysilane.
Methoxytriethyleneoxypropyltrimethoxysilane could be used in the synthesis of more complex organosilicon compounds, such as polysiloxanes. The synthesized polysiloxanes can be widely used in biomedical applications, such as being used as a component of pharmaceutical formulation, participating in drug synthesis, and being used as medical defoaming agent and drug-sustained release material. Methoxytriethyleneoxypropyltrimethoxysilane can also used as PEGylation reagent to form a conjugate with a protein, peptide, drug or other bioactive material by its poly(ethylene glycol) chains to impart desirable properties like increased solubility, resistance to metabolic degradation and reduced immunogenicity to a biomolecule in many instances.
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