Mometasone furoate

CAS

83919-23-7

Catalog Number

ACM83919237

Category

Steroidal Compounds

Molecular Weight

521.44

Molecular Formula

C₂₇H₃₀Cl₂O₆

MSDS COA Spec Sheet

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Specification

Synonyms

Mometasone Furoate; [(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate;

IUPAC Name

[(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]furan-2-carboxylate

Canonical SMILES

CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C

InChI Key

WOFMFGQZHJDGCX-ZULDAHANSA-N

Boiling Point

655.5ºC at 760 mmHg

Melting Point

218-220ºC

Flash Point

350.2ºC

Density

1.37 g/cm³

Appearance

Distributed as 0.1% ointment with a petrolatum base.

EC Number

617-501-0

Exact Mass

614.14700

Stability

Stable if stored as directed.

WGK Germany

What is the molecular formula of Mometasone furoate?

The molecular formula of Mometasone furoate is C27H30Cl2O6.

What is the molecular weight of Mometasone furoate?

The molecular weight of Mometasone furoate is 521.4 g/mol.

How is Mometasone furoate classified structurally?

Mometasone furoate is classified as a 2-furoate ester, a steroid ester, an 11beta-hydroxy steroid, a 20-oxo steroid, an organochlorine compound, and a 3-oxo-Delta(1),Delta(4)-steroid.

What is the role of Mometasone furoate?

Mometasone furoate has a role as an anti-inflammatory drug and an anti-allergic agent.

What is the affinity of Mometasone furoate to the glucocorticoid receptor compared to dexamethasone?

Mometasone furoate has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone.

How can Mometasone furoate be administered?

Mometasone furoate can be formulated as a dry powder inhaler, nasal spray, and ointment for different indications.

How does Mometasone furoate work at the molecular level?

Mometasone furoate binds to cytoplasmic glucocorticoid receptors and activates gene expression, leading to the synthesis of anti-inflammatory proteins and inhibition of inflammatory mediators.

What is the IUPAC name of Mometasone furoate?

The IUPAC name of Mometasone furoate is [(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate.

What is the InChIKey of Mometasone furoate?

The InChIKey of Mometasone furoate is WOFMFGQZHJDGCX-ZULDAHANSA-N.

What are some other identifiers for Mometasone furoate?

Other identifiers for Mometasone furoate include CAS number 83919-23-7, UNII 04201GDN4R, and ChEMBL ID CHEMBL1161.