Methanesulfonic acid methyl ester

• CAS: 66-27-3
• Catalog Number: ACM66273
• Category: Other Products
• Molecular Weight: 110.13
• Molecular Formula: C₂H₆O₃S
• Synonyms: Methyl mesylate, METHYL METHANESULFONATE, Methylmesilate, as-Dimethyl sulfite, Dimethylsulfonate, as-Dimethyl sulphite, methylmesylate, Methylmethanesulfonate, Methylmethansulfonat, Methyl methansulfonate, Mesilate, Methyl, methylmethane sulfonate, Methyl Mesilate, Mesylate, Methyl, Methyl methanesulphonate, Methylmethanesulphonate, Methanesulfonic acid, methyl ester, Methyl methansulphonate, Methanesulfonic acid methyl ester, methylmethansulphonate
• IUPAC Name: methyl methanesulfonate
• InChI Key: MBABOKRGFJTBAE-UHFFFAOYSA-N
• Boiling Point: 202-203ºC
• Melting Point: 20ºC
• Flash Point: 104ºC
• Density: 1.3
• Appearance: colourless liquid
• Exact Mass: 110.00400
• Hazard Statements: T:Toxic
• H-Bond Acceptor: 3
• H-Bond Donor: 0
• Packing Group: III
• Safety Description: S26-S36/37/39-S45-S53
• Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, strong bases.
• WGK Germany: 3

Synthetic Use

Downstream Synthesis Route 1

• 66-27-3
• 99-05-8

• 51524-84-6

Reference: [1] Journal of Medicinal Chemistry, 2006, vol. 49, # 3, p. 1157 - 1164

Downstream Synthesis Route 2

• 66-27-3

• 2386-57-4

Reference: [1] Patent: US2006/30725, 2006, A1, . Location in patent: Page/Page column 6; 7

Downstream Synthesis Route 3

• 66-27-3
• 63200-54-4

• 129872-81-7

Reference: [1] Patent: WO2012/82997, 2012, A1, . Location in patent: Page/Page column 85

Downstream Synthesis Route 4

• 66-27-3
• 115423-26-2

• 7108-27-2

Reference: [1]Journal of the Indian Chemical Society,2009,vol. 86,p. 841 - 848

Downstream Synthesis Route 5

• 66-27-3
• 81290-20-2

• 421-82-9

Reference: [1]Journal of the American Chemical Society,1997,vol. 119,p. 9804 - 9809

* For details of the synthesis route, please refer to the original source to ensure accuracy.