g418

• CAS: 49863-47-0
• Catalog Number: ACM49863470
• Category: Other Products
• Molecular Weight: 496.55
• Molecular Formula: C₂₀H₄₀N₄O₁₀
• Synonyms: O-2-AMINO-2,7-DIDEOXY-DELTA-GLY-CERO-ALPHA-D-GLUCO-HEPTO-PYRANOSYL[1->4]-O-3-DEOXY-4C-METHYL-3-[METHYL-AMINO]-BETA-L-ARABINOPYRONOSYL-DELTA-STREPTAMINE, DISULFATE SALT;AMINOGLYCOSIDE ANTIBIOTIC;ANTIBIOTIC G418;ANTIBIOTIC G418 DISULFATE;ANTIBIOTIC G418 DISULFATE SALT;GENETICIN DISULFATE;GENETICIN DISULFATE SALT;GENETICIN(R)
• Appearance: white powder
• Hazard Statements: Xn
• Safety Description: 22-24/25

Custom Q&A

What is the molecular formula of G418?

The molecular formula of G418 is C20H40N4O10.

What is the molecular weight of G418?

The molecular weight of G418 is 496.6 g/mol.

What is the IUPAC name of G418?

The IUPAC name of G418 is (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-[(1R)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol.

What is the Canonical SMILES of G418?

The Canonical SMILES of G418 is CC(C1C(C(C(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)O)O.

What is the InChIKey of G418?

The InChIKey of G418 is BRZYSWJRSDMWLG-DJWUNRQOSA-N.

What is the CAS number of G418?

The CAS number of G418 is 49863-47-0.

How does G418 block polypeptide synthesis?

G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

How is resistance to G418 conferred?

Resistance to G418 is conferred by the neo gene from Tn5 encoding an aminoglycoside 3'-phosphotransferase, APH 3' II.

What is the XLogP3-AA value of G418?

The XLogP3-AA value of G418 is -5.8.

What is the topological polar surface area of G418?

The topological polar surface area of G418 is 248 Å2.