1-(4-Chlorophenylsulfonyl)-3-propylurea

The molecular formula of chlorpropamide is C10H13ClN2O3S.

The molecular weight of chlorpropamide is 276.74 g/mol.

The IUPAC Name of chlorpropamide is 1-(4-chlorophenyl)sulfonyl-3-propylurea.

The InChIKey of chlorpropamide is RKWGIWYCVPQPMF-UHFFFAOYSA-N.

The canonical SMILES for chlorpropamide is CCCNC(=O)NS(=O)(=O)C1=CC=C(C=C1)Cl.

Chlorpropamide is used as an oral antihyperglycemic agent for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).

Some synonyms for chlorpropamide include Diabinese and Chloropropamid.

Up to 80% of the single oral dose of chlorpropamide is metabolized, likely in the liver, and 80-90% of the dose is excreted in urine as unchanged drug and metabolites.

Chlorpropamide is associated with weight gain, hypoglycemia, increased blood pressure, and the risk of retinopathy.

Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy, as well as causing hypoglycemia which requires consistent food intake to decrease this risk.