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Structure

4-Hydroxy-1,5-naphthyridine

CAS
5423-54-1
Catalog Number
ACM5423541
Category
Other Products
Molecular Weight
146.15
Molecular Formula
C8H6N2O

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Specification

Synonyms
[1,5]NAPHTHYRIDIN-4-OL;4-HYDROXY-1,5-NAPHTHYRIDINE
Density
1.267g/cm³

Upstream Synthesis Route 1

  • 25063-68-7
  • 5423-54-1

Reference: [1] Journal of Medicinal Chemistry, 2017, vol. 60, # 4, p. 1343 - 1361
[2] European Journal of Medicinal Chemistry, 2019, p. 32 - 50

Upstream Synthesis Route 2

  • 1018812-89-9
  • 5423-54-1

Reference: [1] Patent: WO2007/113548, 2007, A1, . Location in patent: Page/Page column 150

Upstream Synthesis Route 3

  • 25063-68-7
  • 53454-31-2
  • 5423-54-1

Reference: [1] Journal of the American Chemical Society, 2009, vol. 131, # 2, p. 763 - 777

Upstream Synthesis Route 4

  • 25063-68-7
  • 53454-31-2
  • 5423-54-1

Reference: [1]Journal of the American Chemical Society,2009,vol. 131,p. 763 - 777

Downstream Synthesis Route 1

  • 5423-54-1
  • 792173-99-0

Reference: [1]Porter, Roderick A; Chan, Wai N; Coulton, Steven; Johns, Amanda; Hadley, Michael S; Widdowson, Katherine; Jerman, Jeffrey C; Brough, Stephen J; Coldwell, Martyn; Smart, Darren; Jewitt, Frances; Jeffrey, Phillip; Austin, Nigel
[Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 14, p. 1907 - 1910]
[2]McElhinny Jr., Charles J.; Lewin, Anita H.; Mascarella, S. Wayne; Runyon, Scott; Brieaddy, Lawrence; Carroll, F. Ivy
[Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 21, p. 6661 - 6664]

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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