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Structure

Bendamustine intermediate

CAS
3543-73-5
Catalog Number
ACM3543735
Category
Other Products
Molecular Weight
261.32
Molecular Formula
C14H19N3O2

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Specification

Synonyms
1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl ester
Appearance
Brown Solid

Upstream Synthesis Route 1

  • 3543-72-4
  • 3543-73-5

Reference: [1] Journal of Labelled Compounds and Radiopharmaceuticals, 2018, vol. 61, # 11, p. 869 - 874
[2] Patent: US2014/31560, 2014, A1, . Location in patent: Paragraph 0103; 0104; 0105; 0106
[3] Patent: WO2012/7966, 2012, A2, . Location in patent: Page/Page column 4
[4] Patent: US2013/317234, 2013, A1, . Location in patent: Paragraph 0023
[5] Patent: EP2690096, 2014, A1, . Location in patent: Paragraph 0075; 0076; 0077; 0078

Upstream Synthesis Route 2

  • 369-36-8
  • 3543-73-5

Reference: [1] Patent: US2014/31560, 2014, A1,

Upstream Synthesis Route 3

  • 108-55-4
  • 3543-73-5

Reference: [1] Patent: US2014/31560, 2014, A1,

Downstream Synthesis Route 1

  • 20195-22-6
  • 3543-73-5
  • 1227860-30-1

Reference: [1]Bioorganic and Medicinal Chemistry,2010,vol. 18,p. 2394 - 2401

Downstream Synthesis Route 2

  • 3543-73-5
  • 107-07-3
  • 3543-74-6

Reference: [1]Patent: WO2012/7966,2012,A2 .Location in patent: Page/Page column 4-5

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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