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Structure

tert-Butyl 1-oxa-5-azaspiro[2.4]heptane-5-carboxylate

CAS
301226-25-5
Catalog Number
ACM301226255
Category
Other Products
Molecular Weight
199.25
Molecular Formula
C10H17NO3

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Specification

Synonyms
1-OXA-5-AZASPIRO[2.4]HEPTANE-5-CARBOXYLIC ACID, 1,1-DIMETHYLETHYL ESTER;tert-Butyl 1-oxa-5-azaspiro[2.4]heptane-5-carboxylate;tert-Butyl 1-oxa-5-azaspiro[2,4]heptane-5-carboxyate
IUPAC Name
tert-butyl 1-oxa-6-azaspiro[2.4]heptane-6-carboxylate
InChI Key
ZFNBSKYWLUKRRV-UHFFFAOYSA-N
Exact Mass
199.12100
H-Bond Acceptor
3
H-Bond Donor
0

Upstream Synthesis Route 1

  • 114214-71-0
  • 301226-25-5

Reference: [1] Journal of Medicinal Chemistry, 2018, vol. 61, # 21, p. 9738 - 9755
[2] Patent: WO2015/35278, 2015, A1, . Location in patent: Page/Page column 89
[3] Patent: US2017/233339, 2017, A1,

Upstream Synthesis Route 2

  • 1774-47-6
  • 101385-93-7
  • 301226-25-5

Reference: [1] Patent: WO2013/138210, 2013, A1, . Location in patent: Paragraph 0209

Downstream Synthesis Route 1

  • 301226-25-5
  • 100-46-9
  • 1072828-07-9

Reference: [1]Patent: US2011/39823,2011,A1 .Location in patent: Page/Page column 59

Downstream Synthesis Route 2

  • 23981-26-2
  • 301226-25-5
  • 1221275-98-4

Reference: [1]Patent: WO2010/41218,2010,A2 .Location in patent: Page/Page column 56

Downstream Synthesis Route 3

  • 301226-25-5
  • 128676-94-8
  • 1243531-84-1

Reference: [1]Tetrahedron Letters,2010,vol. 51,p. 4350 - 4353

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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