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Structure

Ethyl 4-methyl-2-[4-(trifluoromethyl)phenyl]thiazole-5-carboxylate

CAS
175277-03-9
Catalog Number
ACM175277039
Category
Other Products
Molecular Weight
315.31
Molecular Formula
C14H12F3NO2S

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Upstream Synthesis Route 1

  • 72505-21-6
  • 609-15-4
  • 175277-03-9

Reference: [1]European Journal of Medicinal Chemistry,2019,vol. 164,p. 352 - 365

Downstream Synthesis Route 1

  • 175277-03-9
  • 317318-97-1

Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 9, p. 1517 - 1521
[2] European Journal of Medicinal Chemistry, 2016, vol. 113, p. 246 - 257

Downstream Synthesis Route 2

  • 175277-03-9
  • 439134-78-8

Reference: [1] Journal of Medicinal Chemistry, 2007, vol. 50, # 4, p. 685 - 695

Downstream Synthesis Route 3

  • 175277-03-9
  • 317318-96-0

Reference: [1]Current Patent Assignee: KALYPSYS, INC. - WO2005/60958, 2005, A1
Location in patent: Page/Page column 115-116

Downstream Synthesis Route 4

  • 175277-03-9
  • 144059-86-9

Reference: [1]Adams, Luke A.; Sharma, Pooja; Mohanty, Biswaranjan; Ilyichova, Olga V.; Mulcair, Mark D.; Williams, Martin L.; Gleeson, Ellen C.; Totsika, Makrina; Doak, Bradley C.; Caria, Sofia; Rimmer, Kieran; Horne, James; Shouldice, Stephen R.; Vazirani, Mansha; Headey, Stephen J.; Plumb, Brent R.; Martin, Jennifer L.; Heras, Begoca; Simpson, Jamie S.; Scanlon, Martin J.
[Angewandte Chemie - International Edition, 2015, vol. 54, # 7, p. 2179 - 2184][Angew. Chem., 2015, vol. 127, # 7, p. 2207 - 2212]

* For details of the synthesis route, please refer to the original source to ensure accuracy.

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