Fmoc-Gla(OtBu)2-OH

CAS

111662-64-7

Catalog Number

ACM111662647-1

Category

Amino Acids

Molecular Weight

525.59

Molecular Formula

C29H35NO8

MSDS COA Spec Sheet

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Specification

Description

Fmoc-Gla(OtBu)2-OH is a building block for the introduction of γ-carboxyglutamic acid (Gla). γ-Carboxylation of glutamic acid is a rare post-translational modification that occurs in blood coagulation factors and in some snake and cone snail venoms.

Synonyms

Fmoc-Gla(OtBu)2-OH, Fmoc-γ-carboxy-Glu(OtBu) 2-OH, Fmoc-gamma-carboxy-L-glutamic acid gamma,gamma-di-t-butyl ester

InChI

1S/C29H35NO8/c1-28(2,3)37-25(33)21(26(34)38-29(4,5)6)15-23(24(31)32)30-27(35)36-16-22-19-13-9-7-11-17(19)18-12-8-10-14-20(18)22/h7-14,21-23H,15-16H2,1-6H3,(H,30,35)(H,31,32)/t23-/m0/s1

InChI Key

XJRUHYXXHXECDI-QHCPKHFHSA-N

Application

Peptide synthesis.

Form

solid

Functional Group

carboxylic acid

Quality Level

200

Reaction Suitability

reaction type: Fmoc solid-phase peptide synthesis