Sematilide hydrochloride

CAS

101526-62-9

Catalog Number

ACM101526629-1

Category

Others

Molecular Weight

349.87

Molecular Formula

C14H24ClN3O3S

MSDS COA Spec Sheet

If you have any other questions or need other size, please get a quote.

Specification

Description

Sematilide, also known as CK-1752, is a class III antiarrhythmic. It is a selective delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the prolongation of action potential duration and refractoriness.

Synonyms

Sematilide hydrochloride; Sematilide HCl; Sematilide hydrochloride; Sematilide; CK-1752A; CK1752A; CK 1752A; CK-1752; CK1752; CK 1752

IUPAC Name

Benzamide, N-(2-(diethylamino)ethyl)-4-((methylsulfonyl)amino)-, monohydrochloride

Canonical SMILES

O=C(NCCN(CC)CC)C1=CC=C(NS(=O)(C)=O)C=C1.[H]Cl

InChI

InChI=1S/C14H23N3O3S.ClH/c1-4-17(5-2)11-10-15-14(18)12-6-8-13(9-7-12)16-21(3,19)20;/h6-9,16H,4-5,10-11H2,1-3H3,(H,15,18);1H

InChI Key

OKXAJGDKHKNFAX-UHFFFAOYSA-N

Solubility

Soluble in DMSO

Appearance

Solid powder

Shelf Life

>2 years if stored properly

Storage

Dry, dark and at 0-4 °C for short term (days to weeks) or -20 °C for long term (months to years).

Alternative CAS

101526-83-4 (free base); 101526-62-9 (HCl)

Drug Formulation

This drug may be formulated in DMSO

Elemental Analysis

C, 48.06; H, 6.91; Cl, 10.13; N, 12.01; O, 13.72; S, 9.16

HS Tariff Code

2934.99.9001

Shipping

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Stock Solution Storage

0-4 °C for short term (days to weeks), or -20 °C for long term (months).