6-Chloroindole-2-carboxylic acid

• CAS: 16732-75-5
• Catalog Number: ACM16732755
• Category: Indoles
• Molecular Weight: 195.60
• Molecular Formula: C9H6ClNO2
• Synonyms: 6-Chloroindole-2-Carboxylic acid;6-Chloro-1H-indole-2-carboxylic acid;6-Chloroindole-2-carboxylic?acid;6-Chloro indole-2-carboxylic acid;6-Chloroindole-2-carboxylicacid
• Boiling Point: 449.7 °C at 760mmHg
• Flash Point: 225.8 °C
• Density: 1.548 g/cm³

Synthetic Use

Upstream Synthesis Route 1

• 71300-08-8

• 16732-75-5

Reference: [1]Fox; Bullock
[Journal of the American Chemical Society, 1951, vol. 73, p. 2756,2758]
Rydon; Tweddle
[Journal of the Chemical Society, 1955, p. 3499,3502]
[2]Fagan, Gay P.; Chapleo, Christopher B.; Lane, Anthony C.; Myers, Malcolm; Roach, Alan G.; et al
[Journal of Medicinal Chemistry, 1988, vol. 31, # 5, p. 944 - 948]

Downstream Synthesis Route 1

• 16732-75-5

• 17422-33-2

Reference: [1] Journal of the Chemical Society, 1955, p. 3499,3502

Downstream Synthesis Route 2

• 16732-75-5
• 64-17-5

• 27034-51-1

Reference: [1] Journal of Medicinal Chemistry, 1988, vol. 31, # 5, p. 944 - 948

Downstream Synthesis Route 3

• 16732-75-5

• 27034-51-1

Reference: [1] Gazzetta Chimica Italiana, 1958, vol. 88, p. 1147,1153, 1159

Downstream Synthesis Route 4

• 16732-75-5

• 17422-33-2

Reference: [1]Rydon; Tweddle
[Journal of the Chemical Society, 1955, p. 3499,3502]

Downstream Synthesis Route 5

• 16732-75-5
• 64-17-5

• 27034-51-1

Reference: [1]Fagan, Gay P.; Chapleo, Christopher B.; Lane, Anthony C.; Myers, Malcolm; Roach, Alan G.; et al
[Journal of Medicinal Chemistry, 1988, vol. 31, # 5, p. 944 - 948]
[2]Wang, Lei; Fang, Kun; Cheng, Junfei; Li, Yu; Huang, Yahui; Chen, Shuqiang; Dong, Guoqiang; Wu, Shanchao; Sheng, Chunquan
[Journal of Medicinal Chemistry, 2020, vol. 63, # 2, p. 696 - 713]

* For details of the synthesis route, please refer to the original source to ensure accuracy.