3-Chloro-4-hydroxyphenylacetic acid

• CAS: 33697-81-3
• Catalog Number: ACM33697813
• Category: Other Products
• Molecular Weight: 186.59
• Molecular Formula: C₈H₇ClO₃
• Synonyms: (3-chloro-4-hydroxyphenyl)-aceticaci;3-chloro-4-hydroxy-benzeneaceticaci;3-chloro-4-hydroxybenzeneaceticacid;4-hcpa;4-hydroxy-3-chlorophenylaceticacid;kyselina3-chlor-4-hydroxyfenyloctova;vufb9649;3-CHLORO-4-HYDROXYPHENYLACETIC ACID
• IUPAC Name: 2-(3-chloro-4-hydroxyphenyl)acetic acid
• Canonical SMILES: C1=CC(=C(C=C1CC(=O)O)Cl)O
• InChI Key: IYTUKSIOQKTZEG-UHFFFAOYSA-N
• Boiling Point: 348.6ºC at 760mmHg
• Melting Point: 108-110°C(lit.)
• Flash Point: 164.6ºC
• Density: 1.466g/cm³
• EC Number: 251-643-0
• Exact Mass: 186.00800
• Hazard Statements: Xi
• H-Bond Acceptor: 3
• H-Bond Donor: 2
• Safety Description: 26-37/39-36
• Supplemental Hazard Statements: H315-H319-H335
• Symbol: GHS07
• WGK Germany: 2

Synthetic Use

Upstream Synthesis Route 1

• 156-38-7

• 33697-81-3
• 89894-49-5

Reference: [1]D'Ambrosio; Guerriero; Pietra
[Helvetica Chimica Acta, 1984, vol. 67, # 6, p. 1484 - 1492]
[2]D'Ambrosio; Guerriero; Pietra
[Helvetica Chimica Acta, 1984, vol. 67, # 6, p. 1484 - 1492]

Downstream Synthesis Route 1

• 33697-81-3

• 50972-63-9

Reference: [1]Sato; Kawashima; Goto; Yamane; Chiba; Jinno; Satake; Imanishi; Iwata
[Chemical and Pharmaceutical Bulletin, 1994, vol. 42, # 3, p. 521 - 529]
[2]Tanaka, Nobuyuki; Tamai, Tetsuro; Mukaiyama, Harunobu; Hirabayashi, Akihito; Muranaka, Hideyuki; Ishikawa, Takehiro; Kobayashi, Junichi; Akahane, Satoshi; Akahane, Masuo
[Journal of medicinal chemistry, 2003, vol. 46, # 1, p. 105 - 112]

Downstream Synthesis Route 2

• 33697-81-3

• 93245-87-5

Reference: [1]D'Ambrosio; Guerriero; Pietra
[Helvetica Chimica Acta, 1984, vol. 67, # 6, p. 1484 - 1492]

* For details of the synthesis route, please refer to the original source to ensure accuracy.