3-Bromo-2-fluorophenol

• CAS: 156682-53-0
• Catalog Number: ACM156682530
• Category: Bromine Series
• Molecular Weight: 190.9977632
• Molecular Formula: C₆H₄BrFO
• Synonyms: 3-BROMO-2-FLUOROPHENOL, 3-Bromo-2-fluoro-phenol, 156682-53-0, Phenol, bromofluoro-, PubChem16947, 3-Bromo-2-fluorophenol,, ACMC-1C8AS, AGN-PC-01VIDZ, SureCN1067491, Phenol, 3-bromo-2-fluoro-, KSC152Q5L, CTK0F2855, MolPort-001-771-914, ANW-21642, CL8470, FC1188, PC1687, SBB091226, ZINC16158469, AKOS006345495
• IUPAC Name: 3-bromo-2-fluorophenol
• Canonical SMILES: C1=CC(=C(C(=C1)Br)F)O
• InChI Key: MEZFCUMYQXLFOV-UHFFFAOYSA-N
• Boiling Point: 207.4ºC at 760mmHg
• Flash Point: 79.2ºC
• Density: 1.764g/cm³
• Exact Mass: 189.94300
• Hazard Statements: T: Toxic;Xi: Irritant
• H-Bond Acceptor: 2
• H-Bond Donor: 1

Synthetic Use

Upstream Synthesis Route 1

• 38573-88-5

• 156682-53-0
• 2040-89-3

Reference: [1] Synlett, 2009, # 4, p. 633 - 637

Upstream Synthesis Route 2

• 38573-88-5

• 156682-53-0
• 2040-89-3

Reference: [1]Synlett,2009,p. 633 - 637

Downstream Synthesis Route 1

• 156682-53-0
• 1895-39-2

• 1242249-28-0

Reference: [1]Current Patent Assignee: AUTOBAHN THERAPEUTICS - WO2020/180624, 2020, A1
Location in patent: Page/Page column 120-121
[2]Current Patent Assignee: BAYER AG - WO2011/76687, 2011, A1
Location in patent: Page/Page column 182
[3]Current Patent Assignee: MERCK & CO INC - WO2018/107415, 2018, A1
Location in patent: Page/Page column 38
[4]Current Patent Assignee: HANGZHOU INNOGATE PHARMA CO LTD - CN113200981, 2021, A
Location in patent: Paragraph 0238-0241

* For details of the synthesis route, please refer to the original source to ensure accuracy.